×
The Handbook of Microbial Metabolism of Amino Acids
Edited by J. P. F. D'Mello
Hardback
June 2017
9781780647234
More details
- Publisher
CABI - Published
2nd June 2017 - ISBN 9781780647234
- Language English
- Pages 560 pp.
- Size 6.75" x 9.5"
$361.80
This book collates and reviews recent advances in the microbial metabolism of amino acids, emphasizing diversity -- in terms of the range of organisms under investigation and their natural ecology -- and the unique features of amino acid metabolism in bacteria, yeasts, fungi, protozoa and nematodes. As well as studying the individual amino acids, including arginine, sulfur amino acids, branched-chain amino acids and aromatic amino acids, a number of themes are explored throughout the work. These include:
* Comparative issues between the metabolism of microbes and those of higher organisms, including plants and mammals
* Potential for drug targets in pathways of both biosynthesis and degradation of amino acids
* Relationship between amino acids or associated enzymes and virulence in parasitic pathogens
* Practical implications for food microbiology and pathogen characterization
* Future priorities relating to fundamental biochemistry of microrganisms, food quality and safety, human and animal health, plant pathology, drug design and ecology
As the volume of research into the metabolism of amino acids grows, this comprehensive study of the subject is a vital tool for researchers in the fields of biological, medical and veterinary sciences, including microbiology, biochemistry, genetics and pathology. This book is also essential for corporate organizations with active research and development programs, such as those in the pharmaceutical industry.
Section I. Glutamate
1. Structural and Functional Properties of Glutamate Dehydrogenases in Microorganisms—S.Brown and D.C Simcock
2. Glutamate Decarboxylase in Bacteria—Professor D. Debiase
3. The GABA Shunt in Yeast—Professor R. Locy
Section II. Lysine, Arginine and Hydroxyproline
4. Lysine Biosynthesis in Microorganisms— A.O. Hudson, M.A. Savka and R.C. Dobson
5. Arginine Deiminase in Microorganisms—F. Leroy
6. Arginase and Microbial Pathogenesis—R. Lucas
7. Arginine and Methionine as Precursors of Polyamines in Trypanosomatids— Y. Pérez-Pertejo & R. Balaña-Fouce
8. Ornithine and Lysine Decarboxylation in Bacteria—P. Lucas
9. Nitric Oxide Signalling in Yeast—P. Ludovico and F. Rodrigues
10. Hydroxyproline Metabolism in Microorganisms—S. Watanabe
Section III. Serine and Threonine Metabolism
11. Cellular Responses to Serine in Yeast—I.W. Dawes
12. Threonine Degradation in Hyperthermophilic Microorganisms—N. Rashid & M. Akhtar
Section IV. Sulphur Amino Acid Metabolism
13. Methionine Synthesis in Microbes—W. Ziebuhr
14. Methionine Salvage Cycle in Microbes—K.W.Ellens
15. Regulation of Sulphur Amino Acid Metabolism in Fungi—J.V. Paietta
Part V: Branched-Chain Amino Acids
16. Insight into O-Acetylserine Sulfhydrylase Structure, Function and Biopharmaceutical Applications—B. Campanini and A. Mozzarelli
17. Microbial Biosynthesis of Branched-Chain Amino Acids—Y. Ji
18. Metabolic Engineering for L-Valine Production in Corynebacterium glutamicum—X. Wang
19. Flavour Formation from Leucine in Bacteria—M-I Afazal
Section VI. Metabolism of Aromatic and Heterocyclic Amino Acids
20. Microbial Biosynthesis of Phenolic Amino Acids—G. Winter
21. Microbial Degradation of Phenolic Amino Acids—D. Holmes
22. Tryptophan Biosynthesis in Microorganisms: Pathways, Regulation and Comparative Aspects—E.J. Parker
23. Tryptophan Biosynthesis in Bacteria: Drug Targets and Immunology— J.S. Lott
24. The Kynurenine Pathway of Tryptophan Metabolism in Microorganisms—R.S. Phillips
25. Histidine Biosynthesis in Microbes—M.A. Aklujkar,
26. Histidine Degradation in Bacteria—R. A. Bender
27. Histidine Phosphatase Superfamily in Pathogenic Bacteria—P. Palittapongarnpim
Section VII. D-Amino Acids
28. The Functions and Metabolism of D-Amino Acids in Microorganisms—S. Takahashi
29. D-Amino Acid Dehydrogenase in Bacteria—C-D. Lu
30. Utilization of D-Amino Acids by Higher Animals—J.P.F.D’Mello
31. Carbon Sources for Amino Acid-Producing Bacteria—G. Seibold
32. Biofilm Formation: Amino Acid Biomarkers in Candida albicans—C. Yingying
33. Microbial degradation of amino acids in anoxic environments—A. Parthasarathy
34. Amino Acid Metabolism in Helminths—H.V.Simpson & Dr. S.Umair
35. Working Together: Amino Acid Biosynthesis in Endosymbiont harbouring Trypanosomatidae—J.M.P. Alves
36. Rhizobial Amino Acid Metabolism: Polyamine Biosynthesis and Functions—M.F. Dunn
37. Utilization of N-Methylated Amino Acids by Bacteria—M. Wargo
Section IX. Conclusions
38. Recent Advances Underpinning Innovative Strategies for the Future—J.P.F. D’Mello
J. P. F. D'Mello
J.P.F. D’Mello is a double graduate of the University of Nottingham, obtaining a BSc Honors in 1964 and a PhD in 1967, both in the Department of Applied Biochemistry. He began work at the Edinburgh School of Agriculture in 1968, lecturing to students and commencing research with grants from the Agricultural Research Council, Tropical Products Institute (ODA), BP and ICI. He has supervised a number of Honors, MSc and PhD students during his years at Edinburgh, published extensively in refereed journals, and took charge of the Environmental Protection and Management degree course for four years until retirement. Since retiring, he has edited 5 books for CABI, with A Handbook of Environmental Toxicology: Human Disorders and Ecotoxicology published in December 2019 and the authored text Introduction to Environmental Toxicology publishing in late 2020.